Alpha Kappa Alpha Sorority, Incorporated was founded on the campus of Howard University on January 15, 1908, and incorporated as a national organization on January 29, 1913.  ​

The Delta Sigma Omega Chapter is the 21st graduate chapter, of the Alpha Kappa Alpha Sorority organized at Maryland State College (now University of Maryland Eastern Shore) located in Princess Anne, Maryland on December 20, 1947 under direction of North Atlantic Regional Director, Sophia Fowler of Washington, D.C. and the Twelfth Supreme Basileus, Edna Over Gray Campbell. The chapter’s charter members included Hattie W. Brown*; Ermein W. Jackson; Donzelle F. Hutt*; Sylvia F. Small, Shelba S. Small; Esther M. Tilghman; and Inez C. Harewood.

The group’s first initiation was held on April 17, 1948, when they admitted seven members to complete its requirement for a chapter. These members were Bessie B. Small; Laney E. Calhoun; Rose H. Martin; Emma Ore; Portia F. Lewis; Ethel S. Cottman and Annette Williams.

Delta Sigma Omega Chapter continues to support the objectives of Alpha Kappa Alpha Sorority, Inc. under the leadership of its 25 past and present presidents. DSO has carried the torch and triumphed in its efforts to improve the social and economic status of the Maryland Eastern Shore communities, to cultivate and encourage high scholastic achievement, leadership development and ethical standards among African American women.